Pharmacological and Clinical Evidence for the Use of Low- Molecular-Weight Heparins in Acute Coronary Syndromes
نویسندگان
چکیده
Hospital de Clínicas de Porto Alegre and Faculdade de Medicina da Universidade Federal do Rio Grande do Sul Mailing address: Guido Aranha Rosito Serviço de Cardiologia Hospital de Clínicas de Porto Alegre Rua Ramiro Barcelos, 2350 90035-007 Porto Alegre, RS, Brazil, E-mail: [email protected] English version by Stela Maris C. e Gandour Guido Aranha Rosito, Otávio Berwanger da Silva, Jorge Pinto Ribeiro
منابع مشابه
Anticoagulants in heart disease: current status and perspectives.
List of abbreviations . . . . . . . . . . . . . . . . . . 2 Preamble: purposes and scope of the task force . . 2 Blood coagulation . . . . . . . . . . . . . . . . . . . . 3 Haemostasis . . . . . . . . . . . . . . . . . . . . . 3 Arterial thrombosis . . . . . . . . . . . . . . . . . 3 Tissue factor . . . . . . . . . . . . . . . . . . . . . 3 Tissue factor pathway inhibitor . . . . . . . . . . 3 ...
متن کاملLow-molecular-weight heparins in the management of acute coronary syndromes.
Acute coronary syndromes (unstable angina and non-Q-wave myocardial infarction) are caused by the rupture of an atherosclerotic plaque, platelet activation, and fibrin deposition resulting in thrombosis. Aspirin and unfractionated heparin have traditionally been the treatments of choice for patients with acute coronary syndromes. Low-molecular-weight heparins offer potential advantages over unf...
متن کاملLow-molecular-weight heparins for the treatment of acute coronary syndromes.
Low-molecular-weight heparins (LMWHs) possess several advantages over unfractionated heparin (UFH) for the treatment of acute coronary syndromes (ACSs). Already a class I indication for the treatment of unstable angina/non-ST elevation myocardial infarction (UA/NSTEMI), LMWHs also show promise in the setting of ST elevation myocardial infarction (STEMI) and percutaneous coronary intervention (P...
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Antithrombotic treatment is of proven importance in patients with acute coronary syndromes. There is now accumulating evidence from several clinical trials in patients with unstable angina pectoris that the low molecular weight heparins (LMWHs) are at least as effective as unfractionated heparin. The LMWHs are easier to use, with the potential to facilitate long-term outpatient treatment. The r...
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This article will review the results of recent clinical trials evaluating low molecular weight heparins (LMWHs) in the management of patients with acute coronary syndromes of unstable angina and non-ST segment elevation MI. Low molecular weight heparins are a new class of anticoagulants that have a number of advantages over unfractionated heparin (UFH) leading to their increasing use for thromb...
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تاریخ انتشار 2001